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Navigating Multiple Sclerosis: Advances in Cognitive Evaluation and Approaches, Treatment, and Health Equity
Carrie Hersh, DO, MSc, FAAN
Carrie M. Hersh, DO, MSc, FAAN joined the faculty at Cleveland Clinic Lou Ruvo Center for Brain Health (LRCBH) in August 2015 where she also serves as Associate Professor of Neurology at Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She also directs the Multiple Sclerosis (MS) Health and Wellness Program and the Professional Engagement Program and is Associate Program Director of the MS and Neuroimmunology Fellowship at the Cleveland Clinic LRCBH. A patient advocate and proponent of shared decision making, Dr. Hersh specializes in MS and related neuroimmunological disorders. She is particularly interested in real-world evidence, outcomes-based research, comparative effectiveness studies, and understanding the impact of MS and treatments on special populations. She serves as principal investigator of multiple investigator-initiated studies and clinical trials evaluating the effects of disease modifying therapies on clinical, radiographic, and patient-reported outcomes. Dr. Hersh is a frequent lecturer on MS and related disorders topics at national and international meetings and has a prolific publication record, including peer-reviewed scientific journal articles, invited reviews, editorials, abstracts, and book chapters. She is the Editor of the Multiple Sclerosis issue of Neurologic Clinics (February 2024). Dr. Hersh is a leader in the MS community in serving as Chair of the Healthcare Advisory Council for the Multiple Sclerosis Association of America, was the former Chair of the National MS Society’s (NMSS) regional Healthcare Provider Council and currently serves on the NMSS National Medical Advisory Committee, sits on the Board of Governors of the Consortium of MS Centers as Co-Chair of the Scientific Program Committee, and serves on numerous national and international steering committees, expert panels, and advisory boards.
Rachel Galioto, PhD
Dr. Galioto is a board-certified clinical neuropsychologist appointed in the Mellen Center for Multiple Sclerosis Treatment and Research at the Cleveland Clinic and an Assistant Professor of Neurology at Cleveland Clinic Lerner College of Medicine. Her research focuses on various aspects of neurocognitive functioning in patients with multiple sclerosis, other inflammatory demyelinating disorders, and autoimmune encephalitis. In particular, she is interested in the utility and limitations of various neuropsychological measures, factors that may confound the interpretation of cognitive test results, and the development of cognitive phenotyping methods in patients with MS. Her recent work has included examinations of the utility of cognitive screening and performance validity measures in patients with MS, the proposal of a new classification system for cognitive disorders in patients with MS, and a comparison of cognitive profiles between patients with MS and other neurodegenerative diseases.
Credit
CE:1.5
Description
Multiple sclerosis assessment and treatment methods continue to evolve; however, many individuals remain underserved and the implications of inequitable treatment is significant. In this workshop, Dr. Rachel Galioto will provide an overview of updated research on cognition and multiple sclerosis, with a focus on measurement considerations and approaches. Dr. Carrie Hersh will then provide an overview and update on current and emerging treatment strategies and considerations. She will also summarize the importance of real-world evidence in understanding and treating MS, especially for populations of interest that are not well-represented in clinical trials. She will discuss the barriers to care as they relate to social determinants of health and how MS clinicians and researchers can address equitable access to care and participation in clinical research.
As a result of attending this workshop, participants will be able to:
1. Describe expected cognitive profiles within multiple sclerosis and at least one factor which can impact interpretation of results.
As a result of attending this workshop, participants will be able to:
1. Describe expected cognitive profiles within multiple sclerosis and at least one factor which can impact interpretation of results.
2. Discuss current and emerging treatment approaches in multiple sclerosis.
3. Explain the importance of real-world evidence in leveraging multiple sclerosis treatment.
4. Identify current social determinants of health that create barriers to equitable care among underrepresented populations and potential solutions.