Acquired brain injury (ABI) such as traumatic brain injury (TBI) may compromise an individual’s ability to complete their jobs safely. This is critical for certain occupational specialties such as war fighters, aviators, health care, and law enforcement. Individuals in these professions need to be able to perform their duties in complex and dynamic environments and mistakes can impact the lives and safety of themselves and others. ABI can impact their ability to pay attention, think quickly, problem solve, and reason, as well as their overall mental stamina. It is vital that there are proper assessment and rehabilitation practices for those who deal with dangerous material (e.g., explosives), work in extremely volatile environments (e.g., special operation forces), and operate large people transporters (e.g., flight crew and aviators), as well as those in certain leadership roles. Clinicians must consider if any impairments in cognition impact the patient’s cognitive readiness for their specific duties. Traditionally, testing and rehabilitation of cognition in these high-risk occupations has focused on identification of deficits and disability based on civilian models without specific consideration of the advanced and specific cognitive skills needed. This workshop will focus on the cognitive skills required in these high-risk occupations and the cognitive assessments currently used to determine readiness to return to work in specific areas such as the military. The strengths and weaknesses of these standards will be discussed as well as review of the efficacy of cognitive rehabilitation. Results of novel clinical trials for rehabilitation will also be reviewed that may improve our treatment outcomes.